CKDdb-logoCKDdb - Molecule ID A1622

geneAdm
nameADM
speciesMus musculus

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ADML_MOUSEP97297ENSMUSG0000003079011535Mm.1408103275

Functions and classifications

GOC:cytoplasm, C:extracellular space, P:aging, P:androgen metabolic process, P:branching involved in labyrinthine layer morphogenesis, P:cAMP biosynthetic process, P:cAMP-mediated signaling, P:developmental growth, P:female pregnancy, P:G-protein coupled receptor internalization, P:heart development, P:hormone secretion, P:negative regulation of cell proliferation, P:negative regulation of vascular permeability, P:negative regulation of vasoconstriction, P:neural tube closure, P:neuron projection regeneration, P:odontogenesis of dentin-containing tooth, P:organ regeneration, P:positive regulation of angiogenesis, P:positive regulation of apoptotic process, P:positive regulation of cAMP biosynthetic process, P:positive regulation of cell proliferation, P:positive regulation of cytosolic calcium ion concentration, P:positive regulation of heart rate, P:positive regulation of vasculogenesis, P:positive regulation of vasodilation, P:regulation of the force of heart contraction, P:response to cold, P:response to glucocorticoid, P:response to hypoxia, P:response to insulin, P:response to lipopolysaccharide, P:response to starvation, P:response to wounding, P:spongiotrophoblast layer development, P:vascular smooth muscle cell development, P:vasculogenesis
UniProtAmidation, Cleavage on pair of basic residues, Complete proteome, Disulfide bond, Hormone, Reference proteome, Secreted, Signal
PADBsignalling

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp17003339aMus musculus24kidneyglomeruliDiabetes (diabetic nephropathy)1.96< 0.05cDNA microarray17003339
Exp17003339bMus musculus24kidneyglomeruliDiabetes (diabetic nephropathy)2.52< 0.05cDNA microarray17003339
Exp21752957bHomo sapiens22kidneytubuliDiabetes (diabetic kidney disease)0.3< 0.05RNA microarray21752957
Exp23228063Homo sapiens30urinewholePolycystic_Kidney_Disease (Autosomal Dominant Polycystic Kidney disease)0.490.04219LC-MS/MS23228063
Exp23505438aHomo sapiens kidneyproximal tubular cellsDiabetes (diabetic nephropathy)1.510.001cDNA microarray23505438
Exp23505438bHomo sapiens kidneyproximal tubular cellsDiabetes (diabetic nephropathy)1.290.036cDNA microarray23505438
Exp24569379Mus musculus kidneyendothelial cellsAKI (AKI)5.930.000000414RNA microarray24569379

Compile date 08-10-2018© iMODE-CKD consortium