CKDdb-logoCKDdb - Molecule ID A1597

geneAPCS, PTX2
nameSerum amyloid P-component precursor
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
SAMP_HUMANP02743ENSG00000132703325Hs.507080104770

Functions and classifications

GOC:extracellular space, C:protein complex, F:metal ion binding, F:unfolded protein binding, P:acute-phase response, P:chaperone-mediated protein complex assembly, P:protein folding
UniProt3D-structure, Amyloid, Calcium, Complete proteome, Direct protein sequencing, Disulfide bond, Glycoprotein, Lectin, Metal-binding, Polymorphism, Reference proteome, Secreted, Signal
PADBdisease

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionValidationPubMed/DOI
Exp17021608Rattus norvegicus12urineexosomeAKI (AKI)2< 0.05MALDI-TOF-TOF 17021608
Exp17579666bMus musculus6 to 12kidneywholeremnant_kidney_model (remnant kidney model)4.080.05RNA microarray 17579666
Exp19698090aHomo sapiens17bloodmononuclear cellsChronic_Renal_Insufficiency (Chronic kidney disease)2.380.0006891RNA microarray 19698090
Exp20007950aRattus norvegicus8corporawholeDiabetes (Diabetes Mellitus-associated Erectile Dysfunction)2.043.90E-04MALDI-TOF, LC-MS/MS 20007950
Exp20007950bRattus norvegicus8corporawholeDiabetes (Diabetes Mellitus-associated Erectile Dysfunction)1.633.90E-04MALDI-TOF, LC-MS/MS 20007950
Exp20926632aRattus norvegicus2kidneywholePolycystic_Kidney_Disease (polycystic kidney disease)3.26< 0.05DNA microarrayRT-PCR20926632
Exp20926632bRattus norvegicus2kidneywholePolycystic_Kidney_Disease (polycystic kidney disease)3.09< 0.05DNA microarray 20926632
Exp22172726Homo sapiens20kidneyglomeruliDiabetes (type 2 diabetic nephropathy)1.830.0001QSTAR Elite LC-MS/MS 22172726
Exp23344851Rattus norvegicus14urineexosomeDiabetes (diabetic nephropathy)4 nLC-ESI-UHR-QToF-MS/MS 23344851
Exp23762862Homo sapiens10kidneyperitoneal dialysateGlomerulonephritis (chronic glomerulonephritis)5.78 +/- 1.09< 0.05LC-MS/MS 23762862
Exp23935909Homo sapiens24bloodmonocytesChronic_Renal_Insufficiency (Chronic kidney disease)0.490.0313915RNA microarray 23935909
Exp25769567Homo sapiens19kidneygraftsChronic_rejection (Chronic_rejection)1.95< 0.05ESI-TOF/TOF 25769567

Compile date 08-10-2018© iMODE-CKD consortium