CKDdb-logoCKDdb - Molecule ID A1594

geneC4BPA, C4BP
nameC4b-binding protein alpha chain precursor
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
C4BPA_HUMANP04003ENSG00000123838722Hs.1012120830

Functions and classifications

GOC:cytoplasm, C:extracellular region, C:plasma membrane, P:complement activation, classical pathway, P:innate immune response, P:regulation of complement activation, C:cytoplasm
UniProt3D-structure, Complement pathway, Complete proteome, Direct protein sequencing, Disulfide bond, Glycoprotein, Immunity, Innate immunity, Polymorphism, Reference proteome, Repeat, Secreted, Signal, Sushi
PADBunknown

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionValidationPubMed/DOI
Exp17579666cMus musculus6 to 12kidneywholeremnant_kidney_model (remnant kidney model)22.670.05RNA microarraysqRT-PCR17579666
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.150.000263RNA microarray 19698090
Exp20812764Homo sapiens13bloodplasmaTransplantation (Acute Renal Allograft Rejection)0.10.4391LC-MS/MS 20812764
Exp21544065aRattus norvegicus17kidney Diabetes (diabetic nephropathy in T1D)1.70.007MALDI-TOF/TOF 21544065
Exp22172726Homo sapiens20kidneyglomeruliDiabetes (type 2 diabetic nephropathy)1.670.01QSTAR Elite LC-MS/MS 22172726
Exp24497609Rattus norvegicus kidneyglomeruliPuromycin_induced (Puromycin nephropathy model)1.52< 0.05LC-MS/MS 24497609
Exp25667632Homo sapiens10kidneybiopsy sectionGlomerulonephritis (membranous nephropathy)0.57< 0.05MALDI-TOF/TOF 25667632

Compile date 08-10-2018© iMODE-CKD consortium