CKDdb-logoCKDdb - Molecule ID A1581

geneAlb, Alb-1, Alb1
nameSerum albumin
speciesMus musculus

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ALBU_MOUSEP07724ENSMUSG0000002936811657Mm.16773103600, 194470

Functions and classifications

GOC:basement membrane, C:cytoplasm, C:extracellular region, C:extracellular space, C:extracellular vesicular exosome, C:protein complex, F:DNA binding, F:drug binding, F:fatty acid binding, F:oxygen binding, F:pyridoxal phosphate binding, F:toxic substance binding, F:zinc ion binding, P:cellular response to starvation, P:hemolysis by symbiont of host erythrocytes, P:maintenance of mitochondrion location, P:negative regulation of apoptotic process, P:positive regulation of circadian sleep/wake cycle, non-REM sleep, P:response to mercury ion, P:response to nutrient, P:response to organic substance, P:response to platinum ion, P:transport
UniProtCleavage on pair of basic residues, Complete proteome, Copper, Direct protein sequencing, Disulfide bond, Lipid-binding, Metal-binding, Phosphoprotein, Reference proteome, Repeat, Secreted, Signal, Zinc
PADBunknown

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionValidationPubMed/DOI
Exp16083269Rattus norvegicus10bloodserumTransplantation (Acute Renal Allograft Rejection)up< 0.05SELDI-MS (CM10, Q10), MALDI-MS/MS 16083269
Exp16372274Homo sapiens25urinewholeGlomerulonephritis (IgA nephropathy)17.6< 0.05MALDI-TOF-MS 16372274
Exp16372274Homo sapiens25urinewholeGlomerulonephritis (IgA nephropathy)41< 0.05MALDI-TOF-MS 16372274
Exp16372274Homo sapiens25urinewholeGlomerulonephritis (IgA nephropathy)87< 0.05MALDI-TOF-MS 16372274
Exp16549904Mus musculus10urinewholeGlomerulonephritis (membranoproliferative glomerulonephritis model)1.39 nano-LC-MS/MS 16549904
Exp17021608Rattus norvegicus12urineexosomeAKI (AKI)1.7< 0.05MALDI-TOF-TOF 17021608
Exp17081055Rattus norvegicus12urinewholeGlomerulonephritis (membranous nephropathy)up< 0.05MALDI 17081055
Exp17081055Rattus norvegicus12urinewholeGlomerulonephritis (membranous nephropathy)up< 0.05MALDI 17081055
Exp17081055Rattus norvegicus12urinewholeGlomerulonephritis (membranous nephropathy)up< 0.05MALDI 17081055
Exp17242005Homo sapiens27urinewholeGlomerulonephritis (IgA nephropathy)4.3 LC-MS/MS 17242005
Exp17301227Homo sapiens13bloodserumFabry (6 months of ERT) 0.2803nanoLC-ESI-MS/MS 17301227
Exp17579666cMus musculus6 to 12kidneywholeremnant_kidney_model (remnant kidney model)267.50.05RNA microarraysqRT-PCR17579666
Exp17616219Rattus norvegicus10urinewholeGlomerulonephritis (Passive Heymann Nephritis)  MALDI-TOF-MSwestern blot, ELISA17616219
Exp17616219Rattus norvegicus10urinewholeGlomerulonephritis (Passive Heymann Nephritis)1.610.0075MALDI-TOF-MSwestern blot, ELISA17616219
Exp17881425Mus musculus12urinewholeGlomerulonephritis (focal segmental glomerulosclerosis)  MALDI-TOF-MS 17881425
Exp17881425Mus musculus12urinewholeGlomerulonephritis (focal segmental glomerulosclerosis)  MALDI-TOF-MS 17881425
Exp18095357Homo sapiens38urinewholeGlomerulonephritis (IgA nephropathy)11.460.0003nano-HPLC-ESI-MS/MS 18095357
Exp18440303Rattus norvegicus20urineglycoproteinsGlomerulonephritis (adriamycin nephropathy and Thy1.1 induced glomerulonephritis)0.73 LC-MS/MS 18440303
Exp20007950aRattus norvegicus8corporawholeDiabetes (Diabetes Mellitus-associated Erectile Dysfunction)1.340.00012MALDI-TOF, LC-MS/MS 20007950
Exp20007950bRattus norvegicus8corporawholeDiabetes (Diabetes Mellitus-associated Erectile Dysfunction)1.560.00012MALDI-TOF, LC-MS/MS 20007950
Exp20019191Homo sapiens18kidneyglomeruliNephrosclerosis (glomerulosclerosis)1.135.52E-06RNA microarray 20019191
Exp20093355Homo sapiens33kidney Fibrosis (Interstitial fibrosis and tubular atrophy)up MS/MS, LTQ LX linear ion trap 20093355
Exp20411046Homo sapiens5kidneycyst fluidPolycystic_Kidney_Disease (Autosomal Dominant Polycystic Kidney disease) < 0.001LC-MS/MS 20411046
Exp20639044aHomo sapiens46urinewholeureteral_obstruction (unilateral uteropelvic junction obstruction)1.31< 0.05LC-MS/MS 20639044
Exp20639044bHomo sapiens46urinewholeureteral_obstruction (unilateral uteropelvic junction obstruction)0.63< 0.05LC-MS/MS 20639044
Exp20812764Homo sapiens13bloodplasmaTransplantation (Acute Renal Allograft Rejection)0.020LC-MS/MS 20812764
Exp21354196Mus musculus24urinewholeCyclosporine_A_induced (cyclosporine A nephrotoxicity)2.47 MS/MS 21354196
Exp21538912aMus musculus10kidneyglomeruliglomerular_disease (glomerular disease)2.061.2E10-6MALDI-TOF/TOF 21538912
Exp21595033aHomo sapiens12urineexosomesGlomerulonephritis (IgA nephropathy)3.850.00442LC-MS/MS 21595033
Exp22498882Homo sapiens10urinewholeGlomerulonephritis (lupus nephritis)3.50.003ESI-Q-TOF MS/MS 22498882
Exp22536212Homo sapiens86urinewholeDiabetes (type 2 diabetic nephropathy)0.360hybrid quadrupole-TOF, LC-MS/MS 22536212
Exp22536212Homo sapiens86urinewholeDiabetes (type 2 diabetic nephropathy)3.090hybrid quadrupole-TOF, LC-MS/MS 22536212
Exp22972526Rattus norvegicus kidneycortexDiabetes (streptozotocin-induced diabetic)1.92< 0.05LC-MS/MS 22972526
Exp23143504Homo sapiens urinewholeAKI (AKI)21.410.002LC-MS/MS 23143504
Exp23228063Homo sapiens30urinewholePolycystic_Kidney_Disease (Autosomal Dominant Polycystic Kidney disease)1.690.00003LC-MS/MS 23228063
Exp23261757Rattus norvegicus12urinewholeGentamicin_induced (chronic sensitization to gentamicin)up< 0.05MALDI-TOF 23261757
Exp23344851Rattus norvegicus14urineexosomeDiabetes (diabetic nephropathy)20.2 nLC-ESI-UHR-QToF-MS/MS 23344851
Exp23464927Homo sapiens10urine Fabry (12 months of ERT)0.76<0.05QTOF MS/MS 23464927
Exp24090408Rattus norvegicus28kidneycortexChronic_Renal_Insufficiency (early_stage_CKD)up 2DE, LC-MS/MS 24090408
Exp24096133cHomo sapiens10urine>10kDaDiabetes (type 1 diabetes with retinopathy and nephropathy)3.99 1DE, MALDI 24096133
Exp24096133eHomo sapiens10urine>10kDaDiabetes (type 1 diabetes with retinopathy and nephropathy vs type 1 diabetes without retinopathy or nephropathy)3.99 1DE, MALDI 24096133
Exp24096133fHomo sapiens10urine>10kDaDiabetes (type 1 diabetes with retinopathy and nephropathy vs type 1 diabetes with retinopathy)3.1 1DE, MALDI 24096133
Exp24497609Rattus norvegicus kidneyglomeruliPuromycin_induced (Puromycin nephropathy model)4.59< 0.05LC-MS/MS 24497609
Exp24569379Mus musculus kidneyendothelial cellsAKI (AKI)2.670.000132RNA microarray 24569379
Exp24761003bRattus norvegicus18kidneymedullaureteral_obstruction (obstructive uropathy)1.12< 0.05LC-MS/MS 24761003
Exp24761003cRattus norvegicus18kidneymedullaureteral_obstruction (obstructive uropathy)0.72< 0.05LC-MS/MS 24761003
Exp24798088Rattus norvegicus kidney AKI (AKI)2.350.001MS/MS 24798088
Exp24798088Rattus norvegicus kidney AKI (AKI)4.280.018MS/MS 24798088
Exp24834312Rattus norvegicus24kidney Diabetes (diabetic nephropathy induced by Streptozotocin)  2-DE, MALDI-TOF-MS 24834312
Exp25666440Homo sapiens23urinesupernatantFabry (naive Fabry patients)4.210.001105nanoLC-ESI-MS/MS 25666440
Exp26317775bHomo sapiens8kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)121.160.002621RNA microarray 26317775

Compile date 08-10-2018© iMODE-CKD consortium