CKDdb-logoCKDdb - Molecule ID A1579

geneKrt14
nameKeratin, type I cytoskeletal 14
speciesMus musculus

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
K1C14_MOUSEQ61781ENSMUSG0000004554516664Mm.439898125595, 131760, 131800, 131900, 148066, 161000, 601001

Functions and classifications

GOC:cell periphery, C:cytoplasm, C:intracellular, C:keratin filament, C:nucleus, F:protein binding, F:structural molecule activity, P:epithelial cell differentiation, P:intermediate filament bundle assembly, P:response to ionizing radiation, P:response to zinc ion
UniProtCoiled coil, Complete proteome, Cytoplasm, Direct protein sequencing, Disulfide bond, Intermediate filament, Keratin, Nucleus, Reference proteome
PADBCell shape (cytoskeleton, cell adhesion, morphology, cell junction, cellular structures, extracellular matrix)

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19836472Mus musculus kidneytubule cellsDiabetes (Diabetic Nephropathy)0.25 LC-MS/MS19836472
Exp22114694Mus musculus6kidneyureterureteral_obstruction (unilateral hydronephrosis)21.3< 0.05RNA microarray22114694
Exp23464927Homo sapiens10urine Fabry (12 months of ERT)1.5<0.05QTOF MS/MS23464927
Exp24096133aHomo sapiens10urine>10kDaDiabetes (type 1 diabetes without retinopathy or nephropathy)1000 1DE, MALDI24096133
Exp24096133dHomo sapiens10urine>10kDaDiabetes (type 1 diabetes with retinopathy vs type 1 diabetes without retinopathy or nephropathy)0 1DE, MALDI24096133
Exp24096133eHomo sapiens10urine>10kDaDiabetes (type 1 diabetes with retinopathy and nephropathy vs type 1 diabetes without retinopathy or nephropathy)0 1DE, MALDI24096133

Compile date 08-10-2018© iMODE-CKD consortium