CKDdb-logoCKDdb - Molecule ID A141C

geneMt1
nameMetallothionein-1
speciesMus musculus

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGene
MT1_MOUSEP02802ENSMUSG0000003176517748Mm.192991

Functions and classifications

GOC:cytoplasm, C:cytosol, C:lysosome, C:nucleus, C:perinuclear region of cytoplasm, F:copper ion binding, F:metal ion binding, F:zinc ion binding, P:cellular metal ion homeostasis, P:cellular response to chromate, P:cellular response to zinc ion, P:cellular zinc ion homeostasis, P:detoxification of copper ion, P:negative regulation of growth, P:negative regulation of neuron apoptotic process, P:nitric oxide mediated signal transduction, C:cytosol, C:lysosome, F:copper ion binding, F:metal ion binding, F:zinc ion binding, P:cellular metal ion homeostasis, P:cellular response to chromate, P:cellular response to zinc ion, P:cellular zinc ion homeostasis, P:detoxification of copper ion, P:nitric oxide mediated signal transduction, C:cytosol, C:lysosome, F:copper ion binding, F:metal ion binding, F:zinc ion binding, P:cellular metal ion homeostasis, P:cellular response to chromate, P:cellular response to zinc ion, P:cellular zinc ion homeostasis, P:detoxification of copper ion, P:nitric oxide mediated signal transduction
UniProt3D-structure, Acetylation, Complete proteome, Direct protein sequencing, Metal-binding, Metal-thiolate cluster, Reference proteome
PADBunknown

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp17003339aMus musculus24kidneyglomeruliDiabetes (diabetic nephropathy)1.61< 0.05cDNA microarray17003339
Exp17003339bMus musculus24kidneyglomeruliDiabetes (diabetic nephropathy)2.79< 0.05cDNA microarray17003339
Exp24569379Mus musculus kidneyendothelial cellsAKI (AKI)3.920.00000006RNA microarray24569379

Compile date 08-10-2018© iMODE-CKD consortium