CKDdb-logoCKDdb - Molecule ID A137C

geneABCC5, MRP5
nameATP-binding cassette, sub-family C (CFTR/MRP), member 5
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
MRP5_HUMANO15440ENSG0000011477010057Hs.368563605251

Functions and classifications

GOC:integral component of plasma membrane, F:ATP binding, F:ATPase activity, coupled to transmembrane movement of substances, F:organic anion transmembrane transporter activity, P:ATP catabolic process, P:carbohydrate metabolic process, P:hyaluronan biosynthetic process, "C:integral component of membrane, P:ATP catabolic process", "C:integral to plasma membrane, C:perinuclear region of cytoplasm, P:hyaluronan biosynthetic process, P:response to insulin stimulus, P:response to lipopolysaccharide", P:response to lipopolysaccharide, "C:integral to membrane, F:ATPase activity, coupled to transmembrane movement of substances"
UniProtAlternative splicing, ATP-binding, Complete proteome, Glycoprotein, Membrane, Nucleotide-binding, Phosphoprotein, Reference proteome, Repeat, Transmembrane, Transmembrane helix, Transport
PADBTP: transport, storage, endocytosis, exocytosis, vesicles

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseBiomarkerFold change in diseaseP-valueDetectionMol. modificationValidationPubMed/DOI
Exp25770168Homo sapiens17bloodmononuclear cellsGlomerulonephritis (IgA nephropathy) 5.280.004RNA microarray  25770168

Compile date 08-30-2016© iMODE-CKD consortium