CKDdb-logoCKDdb - Molecule ID A1370

geneCBX5, HP1A
nameChromobox protein homolog 5
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
CBX5_HUMANP45973ENSG0000009491623468Hs.349283604478

Functions and classifications

GOC:chromocenter, C:cytoplasm, C:histone deacetylase complex, C:histone methyltransferase complex, C:kinetochore, C:nuclear centromeric heterochromatin, C:nuclear envelope, C:nucleolus, C:transcriptional repressor complex, F:chromatin binding, F:methylated histone residue binding, F:protein binding, bridging, F:repressing transcription factor binding, P:blood coagulation, P:negative regulation of transcription, DNA-templated, P:viral process, C:nuclear heterochromatin, P:negative regulation of transcription, DNA-templated, C:nucleus, P:negative regulation of transcription, DNA-dependent, P:virus-host interaction, P:negative regulation of transcription, DNA-dependent
UniProt3D-structure, Centromere, Chromosome, Complete proteome, Direct protein sequencing, Host-virus interaction, Nucleus, Phosphoprotein, Reference proteome, Repeat, Ubl conjugation
PADBtranscription and translation, gene regulation

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19698090aHomo sapiens17bloodmononuclear cellsChronic_Renal_Insufficiency (Chronic kidney disease)0.380.0102473RNA microarray19698090
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.450.000615RNA microarray19698090
Exp24172336Mus musculus6kidneycortexAKI (AKI)10000.049762673LC-MS/MS24172336
Exp24569379Mus musculus kidneyendothelial cellsAKI (AKI)0.330.000000347RNA microarray24569379

Compile date 08-10-2018© iMODE-CKD consortium