CKDdb-logoCKDdb - Molecule ID A136C

geneAbcc4, Abcc4, Abcc4
nameMultidrug resistance-associated protein 4 splice variant
speciesRattus norvegicus

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
MRP4_HUMANQ6QMG5ENSRNOG00000010064170924Rn.13195605250

Functions and classifications

GOC:integral component of membrane, F:ATP binding, F:ATPase activity, coupled to transmembrane movement of substances, C:integral to membrane, P:ATP catabolic process, C:basolateral plasma membrane, C:integral component of membrane, F:ATP binding, F:ATPase activity, coupled to transmembrane movement of substances, P:positive regulation of smooth muscle cell proliferation, P:response to drug, P:response to organic cyclic compound, P:response to organic substance, P:response to organonitrogen compound, C:basolateral plasma membrane, C:integral component of membrane, F:ATP binding, F:ATPase activity, coupled to transmembrane movement of substances, P:positive regulation of smooth muscle cell proliferation, P:response to drug, P:response to organic cyclic compound, P:response to organic substance, P:response to organonitrogen compound, C:integral component of membrane, F:ATP binding, F:ATPase activity, coupled to transmembrane movement of substances, C:integral to membrane, P:ATP catabolic process, C:basolateral plasma membrane, F:ATP binding, F:ATPase activity, P:positive regulation of smooth muscle cell proliferation, P:response to drug, P:response to organic cyclic compound, P:response to organic substance, P:response to organonitrogen compound, P:ATP catabolic process, P:response to organic nitrogen, C:basolateral plasma membrane, C:integral component of membrane, F:ATP binding, F:ATPase activity, coupled to transmembrane movement of substances, P:positive regulation of smooth muscle cell proliferation, P:response to drug, P:response to organic cyclic compound, P:response to organic substance, P:response to organonitrogen compound, C:integral to membrane, P:ATP catabolic process, C:integral to membrane, F:ATP binding, F:ATPase activity, coupled to transmembrane movement of substances, P:ATP catabolic process, C:integral to membrane, F:ATP binding, F:ATPase activity, coupled to transmembrane movement of substances, P:ATP catabolic process
UniProtAlternative splicing, ATP-binding, Complete proteome, Glycoprotein, Membrane, Nucleotide-binding, Phosphoprotein, Polymorphism, Reference proteome, Repeat, Transmembrane, Transmembrane helix, Transport
PADBunknown

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseBiomarkerFold change in diseaseP-valueDetectionMol. modificationValidationPubMed/DOI
Exp20926632aRattus norvegicus2kidneywholePolycystic_Kidney_Disease (polycystic kidney disease) 1.52< 0.05DNA microarray  20926632
Exp20926632bRattus norvegicus2kidneywholePolycystic_Kidney_Disease (polycystic kidney disease) 0.64< 0.05DNA microarray  20926632
Exp21752957bHomo sapiens22kidneytubuliDiabetes (diabetic kidney disease) 2.93< 0.05RNA microarray  21752957
Exp24172336Mus musculus6kidneycortexAKI (AKI) 10000.018792802LC-MS/MS  24172336
Exp26317775bHomo sapiens8kidneybiopsy specimensChronic_Renal_Insufficiency (CKD) 0.250.013999RNA microarray  26317775

Compile date 08-30-2016© iMODE-CKD consortium