CKDdb-logoCKDdb - Molecule ID A1362

geneAdcy7
nameAdenylate cyclase type 7
speciesMus musculus

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ADCY7_MOUSEP51829ENSMUSG0000003165911513Mm.288206600385

Functions and classifications

GOC:integral component of membrane, C:plasma membrane, F:adenylate cyclase activity, F:ATP binding, F:metal ion binding, P:activation of adenylate cyclase activity, P:cAMP biosynthetic process, P:cellular response to ethanol, P:intracellular signal transduction, P:maternal process involved in female pregnancy, C:integral component of membrane, C:plasma membrane, F:adenylate cyclase activity, F:nucleotide binding, P:activation of adenylate cyclase activity, P:cAMP biosynthetic process, P:intracellular signal transduction, C:integral component of membrane, C:plasma membrane, F:adenylate cyclase activity, F:nucleotide binding, P:activation of adenylate cyclase activity, P:cAMP biosynthetic process, P:intracellular signal transduction
UniProtATP-binding, cAMP biosynthesis, Complete proteome, Glycoprotein, Lyase, Magnesium, Membrane, Metal-binding, Nucleotide-binding, Reference proteome, Repeat, Transmembrane, Transmembrane helix
PADBenzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp18187931aMus musculus20kidneyglomeruliGlomerulonephritis (lupus nephritis)25.9< 0.05RNA microarray18187931
Exp18187931bMus musculus18kidneyglomeruliGlomerulonephritis (lupus nephritis)9.8< 0.05RNA microarray18187931
Exp20019191Homo sapiens18kidneyglomeruliNephrosclerosis (glomerulosclerosis)3.127.27E-05RNA microarray20019191
Exp21752957aHomo sapiens22kidneytubuliDiabetes (diabetic kidney disease)5.05< 0.05RNA microarray21752957
Exp23757392aRattus norvegicus17kidneywholeDiabetes (diabetic nephropathy)2.94< 0.05RNA-seq23757392
Exp24569379Mus musculus kidneyendothelial cellsAKI (AKI)0.232.02E-08RNA microarray24569379

Compile date 08-10-2018© iMODE-CKD consortium