CKDdb-logoCKDdb - Molecule ID A134C

geneABCC2, CMOAT, CMOAT1
nameCanalicular multispecific organic anion transporter 1
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
MRP2_HUMANQ92887ENSG000000238391244Hs.368243237500, 601107

Functions and classifications

GOC:apical plasma membrane, C:integral component of plasma membrane, C:intercellular canaliculus, F:ATP binding, F:ATPase activity, coupled to transmembrane movement of substances, F:organic anion transmembrane transporter activity, P:cellular chloride ion homeostasis, P:drug transmembrane transport, P:prostaglandin transport, P:response to arsenic-containing substance, P:response to estrogen, P:response to heat, P:response to methotrexate, P:response to oxidative stress, P:thyroid hormone transport, C:integral to plasma membrane, F:organic anion transmembrane transporter activity
UniProtATP-binding, Complete proteome, Disease mutation, Glycoprotein, Membrane, Nucleotide-binding, Phosphoprotein, Polymorphism, Reference proteome, Repeat, Transmembrane, Transmembrane helix, Transport
PADBtransport, storage, endocytosis, exocytosis, vesicles

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseBiomarkerFold change in diseaseP-valueDetectionMol. modificationValidationPubMed/DOI
Exp19099603cMus musculus6kidneywholePolycystic_Kidney_Disease (Autosomal Dominant Polycystic kidney disease) 0.490.04cDNA microarray  19099603
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis) 0.290.00613RNA microarray  19698090

Compile date 08-30-2016© iMODE-CKD consortium