CKDdb-logoCKDdb - Molecule ID A133C

geneABCC1, MRP, MRP1
nameMultidrug resistance-associated protein 1
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
MRP1_HUMANP33527ENSP000002630144363Hs.391464158343

Functions and classifications

GOC:Golgi apparatus, C:integral component of plasma membrane, C:nucleus, F:ATP binding, F:ATPase activity, coupled to transmembrane movement of substances, P:arachidonic acid metabolic process, P:cobalamin metabolic process, P:leukotriene metabolic process, P:response to drug, C:integral component of membrane, P:ATP catabolic process, C:integral component of plasma membrane, F:homoaconitate hydratase activity, P:ATP catabolic process, P:transport, C:basolateral plasma membrane, C:Golgi apparatus, C:integral to plasma membrane, F:efflux transmembrane transporter activity, F:glutathione S-conjugate-exporting ATPase activity, F:glutathione transmembrane transporter activity, F:lipid-transporting ATPase activity, F:long-chain fatty acid transporter activity, F:sphingolipid transporter activity, F:xenobiotic-transporting ATPase activity, P:cell chemotaxis, P:drug export, P:glutathione transmembrane transport, P:phospholipid efflux, P:plasma membrane long-chain fatty acid transport, P:positive regulation of cell migration, P:response to drug, P:response to oxidative stress, C:integral to membrane, F:ATPase activity, coupled to transmembrane movement of substances, C:basolateral plasma membrane, C:cytoplasm, P:response to oxidative stress
UniProt3D-structure, Alternative splicing, ATP-binding, Cell membrane, Complete proteome, Glycoprotein, Hydrolase, Membrane, Nucleotide-binding, Phosphoprotein, Polymorphism, Reference proteome, Repeat, Transmembrane, Transmembrane helix, Transport
PADBTP: transport, storage, endocytosis, exocytosis, vesicles

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseBiomarkerFold change in diseaseP-valueDetectionMol. modificationValidationPubMed/DOI
Exp21752957aHomo sapiens22kidneytubuliDiabetes (diabetic kidney disease) 4.1< 0.05RNA microarray  21752957

Compile date 08-30-2016© iMODE-CKD consortium