CKDdb-logoCKDdb - Molecule ID A126J

geneATP6V0E2, ATP6V0E2L
nameV-type proton ATPase subunit E 2
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
VA0E2_HUMANQ8NHE4ENSG00000171130155066Hs.556998611019

Functions and classifications

GOC:endosome membrane, C:integral component of membrane, C:phagocytic vesicle membrane, C:proton-transporting V-type ATPase, V0 domain, F:ATPase activity, coupled to transmembrane movement of ions, F:hydrogen ion transmembrane transporter activity, P:ATP hydrolysis coupled proton transport, P:cell growth, P:cellular iron ion homeostasis, P:insulin receptor signaling pathway, P:interaction with host, P:phagosome maturation, P:transferrin transport, P:vacuolar acidification, "C:proton-transporting V-type ATPase, V0 domain, P:ATP hydrolysis coupled proton transport", C:integral to membrane, C:vacuole
UniProtAlternative splicing, Complete proteome, Hydrogen ion transport, Hydrolase, Ion transport, Membrane, Reference proteome, Transmembrane, Transmembrane helix, Transport
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp26317775bHomo sapiens8kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)6.460.006579RNA microarray26317775

Compile date 08-10-2018© iMODE-CKD consortium