CKDdb-logoCKDdb - Molecule ID A123J

geneAVPR1A, AVPR1
nameVasopressin V1a receptor
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
V1AR_HUMANP37288ENSG00000166148552Hs.2131600821

Functions and classifications

GOC:cytoplasmic vesicle, C:endosome, C:integral component of plasma membrane, F:peptide hormone binding, F:protein kinase C binding, F:vasopressin receptor activity, P:activation of phospholipase C activity, P:blood circulation, P:calcium-mediated signaling, P:cellular response to water deprivation, P:generation of precursor metabolites and energy, P:grooming behavior, P:maternal aggressive behavior, P:maternal behavior, P:myotube differentiation, P:negative regulation of female receptivity, P:negative regulation of transmission of nerve impulse, P:penile erection, P:positive regulation of cell growth, P:positive regulation of cell proliferation, P:positive regulation of cellular pH reduction, P:positive regulation of cytosolic calcium ion concentration, P:positive regulation of glutamate secretion, P:positive regulation of heart rate, P:positive regulation of prostaglandin biosynthetic process, P:positive regulation of renal sodium excretion, P:positive regulation of systemic arterial blood pressure, P:positive regulation of vasoconstriction, P:regulation of systemic arterial blood pressure by vasopressin, P:response to corticosterone, P:social behavior, P:sperm ejaculation, P:telencephalon development, C:integral component of membrane, C:integral to plasma membrane, P:elevation of cytosolic calcium ion concentration, P:response to corticosterone stimulus, C:integral to membrane
UniProt3D-structure, Cell membrane, Complete proteome, Disulfide bond, G-protein coupled receptor, Glycoprotein, Lipoprotein, Membrane, Palmitate, Phosphoprotein, Polymorphism, Receptor, Reference proteome, Transducer, Transmembrane, Transmembrane helix
PADBreceptor

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.20.00539RNA microarray19698090
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.440.0139RNA microarray19698090
Exp23935909Homo sapiens24bloodmonocytesChronic_Renal_Insufficiency (Chronic kidney disease)0.310.0392257RNA microarray23935909

Compile date 08-10-2018© iMODE-CKD consortium