CKDdb-logoCKDdb - Molecule ID A1213

geneBMX
nameCytoplasmic tyrosine-protein kinase BMX
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
BMX_HUMANP51813ENSG00000102010660Hs.495731300101

Functions and classifications

GOC:cytosol, C:ruffle membrane, F:ATP binding, F:metal ion binding, F:non-membrane spanning protein tyrosine kinase activity, F:signal transducer activity, P:cell adhesion, P:cellular component disassembly involved in execution phase of apoptosis, P:intracellular signal transduction, P:mesoderm development, P:protein autophosphorylation, P:response to stress, F:protein tyrosine kinase activity, P:peptidyl-tyrosine phosphorylation, F:phospholipid binding, C:intracellular
UniProt3D-structure, Apoptosis, ATP-binding, Cell adhesion, Complete proteome, Cytoplasm, Direct protein sequencing, Kinase, Metal-binding, Nucleotide-binding, Phosphoprotein, Polymorphism, Reference proteome, SH2 domain, Stress response, Transferase, Tyrosine-protein kinase, Zinc, Zinc-finger, Receptor
PADBenzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.320.0147RNA microarray19698090
Exp21411733bMus musculus11macrophageF4/80hi cellsGlomerulonephritis (lupus nephritis)0.470.002cDNA microarray21411733
Exp26317775aHomo sapiens53kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)0.312.37E-03RNA microarray26317775

Compile date 08-10-2018© iMODE-CKD consortium