CKDdb-logoCKDdb - Molecule ID A1198

genePTPRD, BPTP-2
nameProtein-tyrosine phosphatase delta precursor
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
PTPRD_HUMANP23468ENSG000001537075789Hs.446083601598

Functions and classifications

GOC:integral component of plasma membrane, F:cell adhesion molecule binding, F:receptor binding, F:transmembrane receptor protein tyrosine phosphatase activity, P:heterophilic cell-cell adhesion, P:neuron differentiation, P:positive regulation of dendrite morphogenesis, P:presynaptic membrane assembly, P:transmembrane receptor protein tyrosine phosphatase signaling pathway, F:protein tyrosine phosphatase activity, P:peptidyl-tyrosine dephosphorylation, C:integral to plasma membrane
UniProt3D-structure, Alternative splicing, Complete proteome, Disulfide bond, Glycoprotein, Hydrolase, Immunoglobulin domain, Membrane, Polymorphism, Protein phosphatase, Receptor, Reference proteome, Repeat, Signal, Transmembrane, Transmembrane helix
PADBenzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp17003339aMus musculus24kidneyglomeruliDiabetes (diabetic nephropathy)1.25< 0.05cDNA microarray17003339
Exp17003339bMus musculus24kidneyglomeruliDiabetes (diabetic nephropathy)1.87< 0.05cDNA microarray17003339
Exp17579666cMus musculus6 to 12kidneywholeremnant_kidney_model (remnant kidney model)2.380.05RNA microarray17579666
Exp19099603cMus musculus6kidneywholePolycystic_Kidney_Disease (Autosomal Dominant Polycystic kidney disease)0.290cDNA microarray19099603
Exp19099603cMus musculus6kidneywholePolycystic_Kidney_Disease (Autosomal Dominant Polycystic kidney disease)0.340cDNA microarray19099603
Exp19099603dMus musculus6kidneywholePolycystic_Kidney_Disease (Autosomal Dominant Polycystic kidney disease)0.260cDNA microarray19099603
Exp19099603dMus musculus6kidneywholePolycystic_Kidney_Disease (Autosomal Dominant Polycystic kidney disease)0.290cDNA microarray19099603
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.440.0205RNA microarray19698090
Exp21752957aHomo sapiens22kidneytubuliDiabetes (diabetic kidney disease)0.13< 0.05RNA microarray21752957
Exp21752957bHomo sapiens22kidneytubuliDiabetes (diabetic kidney disease)0.13< 0.05RNA microarray21752957
Exp21752957bHomo sapiens22kidneytubuliDiabetes (diabetic kidney disease)0.22< 0.05RNA microarray21752957
Exp21752957bHomo sapiens22kidneytubuliDiabetes (diabetic kidney disease)0.29< 0.05RNA microarray21752957
Exp23935909Homo sapiens24bloodmonocytesChronic_Renal_Insufficiency (Chronic kidney disease)0.170.0035367RNA microarray23935909
Exp24569379Mus musculus kidneyendothelial cellsAKI (AKI)0.490.0142RNA microarray24569379

Compile date 08-10-2018© iMODE-CKD consortium