CKDdb-logoCKDdb - Molecule ID A1183

geneBARD1
nameBRCA1-associated RING domain protein 1
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
BARD1_HUMANQ99728ENSG00000138376580Hs.591642601593

Functions and classifications

GOC:BRCA1-A complex, C:BRCA1-BARD1 complex, C:cytoplasm, F:kinase binding, F:RNA binding, F:ubiquitin-protein ligase activity, F:zinc ion binding, P:cell cycle arrest, P:cellular response to DNA damage stimulus, P:DNA repair, P:negative regulation of apoptotic process, P:negative regulation of mRNA 3'-end processing, P:negative regulation of protein export from nucleus, P:positive regulation of apoptotic process, P:positive regulation of protein catabolic process, P:protein K6-linked ubiquitination, P:regulation of phosphorylation, P:tissue homeostasis, F:metal ion binding, P:response to DNA damage stimulus, P:spermatogenesis
UniProt3D-structure, ANK repeat, Complete proteome, DNA damage, DNA repair, Isopeptide bond, Ligase, Metal-binding, Nucleus, Phosphoprotein, Polymorphism, Reference proteome, Repeat, Ubl conjugation, Ubl conjugation pathway, Zinc, Zinc-finger
PADBenzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp23935909Homo sapiens24bloodmonocytesChronic_Renal_Insufficiency (Chronic kidney disease)4.380.0231635RNA microarray23935909

Compile date 08-10-2018© iMODE-CKD consortium