CKDdb-logoCKDdb - Molecule ID A1106

geneARHGAP6, RHOGAP6
nameRho-GTPase-activating protein 6
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
RHG06_HUMANO43182ENSG00000047648395Hs.435291300118

Functions and classifications

GOC:actin filament, C:cytosol, F:phospholipase activator activity, F:Rho GTPase activator activity, F:SH3/SH2 adaptor activity, P:actin filament polymerization, P:activation of phospholipase C activity, P:focal adhesion assembly, P:negative regulation of focal adhesion assembly, P:negative regulation of stress fiber assembly, P:Rho protein signal transduction, C:intracellular, P:signal transduction, C:actin cytoskeleton, P:actin filament organization
UniProtAlternative splicing, Complete proteome, Cytoplasm, GTPase activation, Phosphoprotein, Polymorphism, Reference proteome, SH3-binding
PADBunknown

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.350.00725RNA microarray19698090
Exp24569379Mus musculus kidneyendothelial cellsAKI (AKI)0.430.00000878RNA microarray24569379

Compile date 08-10-2018© iMODE-CKD consortium