CKDdb-logoCKDdb - Molecule ID A108F

geneATP8B3, ATP1K, FOS37502_2
namePotential phospholipid-transporting ATPase IK
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
AT8B3_HUMANO60423ENSG00000130270148229Hs.306212605866

Functions and classifications

GOC:acrosomal vesicle, C:integral component of membrane, F:ATP binding, F:cation-transporting ATPase activity, F:magnesium ion binding, F:phospholipid-translocating ATPase activity, P:ATP catabolic process, P:binding of sperm to zona pellucida, P:ion transmembrane transport, P:phospholipid translocation, C:acrosomal vesicle, C:integral to membrane, F:ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism, P:cation transport, P:phospholipid translocation
UniProtAlternative splicing, ATP-binding, Complete proteome, Hydrolase, Magnesium, Membrane, Metal-binding, Nucleotide-binding, Polymorphism, Reference proteome, Transmembrane, Transmembrane helix
PADBenzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.210.000111RNA microarray19698090
Exp23935909Homo sapiens24bloodmonocytesChronic_Renal_Insufficiency (Chronic kidney disease)0.390.0382337RNA microarray23935909
Exp26317775bHomo sapiens8kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)0.180.012154RNA microarray26317775

Compile date 08-10-2018© iMODE-CKD consortium