CKDdb-logoCKDdb - Molecule ID A105F

nameDNA-(apurinic or apyrimidinic site) lyase 2
speciesHomo sapiens

Molecule reference


Functions and classifications

GOC:mitochondrial inner membrane, C:nucleus, F:DNA binding, F:DNA-(apurinic or apyrimidinic site) lyase activity, F:endonuclease activity, F:exonuclease activity, F:zinc ion binding, P:cell cycle, P:DNA recombination, P:DNA repair, P:nucleic acid phosphodiester bond hydrolysis, C:intracellular, F:lyase activity, F:nuclease activity, F:metal ion binding
UniProtCell cycle, Complete proteome, Cytoplasm, DNA damage, DNA recombination, DNA repair, DNA-binding, Endonuclease, Exonuclease, Hydrolase, Lyase, Magnesium, Metal-binding, Mitochondrion, Nuclease, Nucleus, Polymorphism, Reference proteome
PADBenzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.50.000092RNA microarray19698090

Compile date 08-10-2018© iMODE-CKD consortium