CKDdb-logoCKDdb - Molecule ID A105B

geneBRF1, BRF, GTF3B
nameTranscription factor IIIB 90 kDa subunit
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
TF3B_HUMANQ92994ENSG000001850242972Hs.424484604902

Functions and classifications

GOC:nucleoplasm, C:transcription factor TFIIIB complex, F:zinc ion binding, P:positive regulation of transcription, DNA-templated, P:regulation of mRNA stability, P:rRNA transcription, P:transcription initiation from RNA polymerase III promoter, P:tRNA transcription, F:zinc ion binding, P:DNA-templated transcription, initiation, P:regulation of transcription, DNA-templated, C:nucleus, F:translation initiation factor activity, P:positive regulation of transcription, DNA-templated, P:regulation of mRNA stability, F:metal ion binding, P:DNA-dependent transcription, initiation, P:positive regulation of transcription, DNA-dependent, P:regulation of transcription, DNA-dependent, P:positive regulation of transcription, DNA-dependent
UniProtActivator, Alternative splicing, Complete proteome, Direct protein sequencing, Metal-binding, Nucleus, Phosphoprotein, Polymorphism, Reference proteome, Repeat, Transcription, Transcription regulation, Zinc, Zinc-finger, Initiation factor, Protein biosynthesis
PADBtranscription and translation, gene regulation

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.470.00932RNA microarray19698090
Exp24172336Mus musculus6kidneycortexAKI (AKI)1.370.022973399LC-MS/MS24172336

Compile date 08-10-2018© iMODE-CKD consortium