CKDdb-logoCKDdb - Molecule ID A0993

geneCAMK4, CAMK, CAMK-GR
nameCalcium/calmodulin-dependent protein kinase type IV catalytic chain
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
KCC4_HUMANQ16566ENSG00000152495814Hs.591269114080

Functions and classifications

GOC:cytosol, C:nucleolus, C:nucleoplasm, F:ATP binding, F:calmodulin-dependent protein kinase activity, P:activation of phospholipase C activity, P:epidermal growth factor receptor signaling pathway, P:fibroblast growth factor receptor signaling pathway, P:inflammatory response, P:innate immune response, P:long-term memory, P:myeloid dendritic cell differentiation, P:neuron-neuron synaptic transmission, P:neurotrophin TRK receptor signaling pathway, P:nucleocytoplasmic transport, P:positive regulation of protein export from nucleus, P:positive regulation of transcription, DNA-templated, P:protein phosphorylation, P:regulation of osteoclast differentiation, P:regulation of T cell differentiation in thymus, P:synaptic transmission, F:protein serine/threonine kinase activity, F:protein kinase activity, C:cytoplasm, C:nucleus, P:signal transduction, P:nerve growth factor receptor signaling pathway, P:positive regulation of transcription, DNA-dependent
UniProt3D-structure, Adaptive immunity, ATP-binding, Calcium, Calmodulin-binding, Complete proteome, Cytoplasm, Glycoprotein, Immunity, Inflammatory response, Kinase, Nucleotide-binding, Nucleus, Phosphoprotein, Polymorphism, Reference proteome, Serine/threonine-protein kinase, Transferase
PADBenzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.410.000627RNA microarray19698090

Compile date 08-10-2018© iMODE-CKD consortium