CKDdb-logoCKDdb - Molecule ID A0935

geneAANAT, SNAT
nameSerotonin N-acetyltransferase
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
SNAT_HUMANQ16613ENSG0000012967315Hs.431417600950, 614163

Functions and classifications

GOC:cytosol, C:perinuclear region of cytoplasm, F:aralkylamine N-acetyltransferase activity, P:cellular response to cAMP, P:circadian rhythm, P:indolalkylamine biosynthetic process, P:melatonin biosynthetic process, P:N-terminal protein amino acid acetylation, P:small molecule metabolic process, C:cytoplasm, F:arylamine N-acetyltransferase activity, P:metabolic process, P:response to calcium ion, P:response to cAMP, P:response to copper ion, P:response to corticosterone, P:response to cytokine, P:response to insulin, P:response to light stimulus, P:response to prostaglandin E, P:response to zinc ion, F:N-acetyltransferase activity, F:transferase activity, P:response to corticosterone stimulus, P:response to cytokine stimulus, P:response to insulin stimulus, P:response to prostaglandin E stimulus
UniProtAcyltransferase, Biological rhythms, Complete proteome, Cytoplasm, Disease mutation, Melatonin biosynthesis, Phosphoprotein, Polymorphism, Reference proteome, Transferase
PADBenzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseBiomarkerFold change in diseaseP-valueDetectionMol. modificationValidationPubMed/DOI
Exp15042541Homo sapiens4kidneyglomeruliDiabetes (diabetic nephropathy) 2.3< 0.01RNA microarray  15042541
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis) 0.250.000102RNA microarray  19698090

Compile date 08-30-2016© iMODE-CKD consortium