CKDdb-logoCKDdb - Molecule ID A0893

geneARIH2, ARI2, TRIAD1
nameAriadne-2 protein homolog
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ARI2_HUMANO95376ENSG0000017747910425Hs.633601605615

Functions and classifications

GOC:cytoplasm, C:nucleus, F:nucleic acid binding, F:ubiquitin-protein ligase activity, F:zinc ion binding, P:developmental cell growth, P:hematopoietic stem cell proliferation, P:protein K48-linked ubiquitination, P:protein K63-linked ubiquitination, P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process, P:ubiquitin-dependent protein catabolic process, F:metal ion binding
UniProtCoiled coil, Complete proteome, Cytoplasm, Ligase, Metal-binding, Nucleus, Phosphoprotein, Polymorphism, Reference proteome, Repeat, Ubl conjugation, Ubl conjugation pathway, Zinc, Zinc-finger
PADBenzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19698090aHomo sapiens17bloodmononuclear cellsChronic_Renal_Insufficiency (Chronic kidney disease)2.460.0006668RNA microarray19698090
Exp26317775aHomo sapiens53kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)3.163.04E-04RNA microarray26317775

Compile date 08-10-2018© iMODE-CKD consortium