CKDdb-logoCKDdb - Molecule ID A0888

geneBcar1, Cas, Crkas
nameBreast cancer anti-estrogen resistance protein 1
speciesMus musculus

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
BCAR1_MOUSEQ61140ENSMUSG0000003195512927Mm.3758602941

Functions and classifications

GOC:cytoplasm, C:focal adhesion, C:lamellipodium, C:plasma membrane, C:ruffle, F:protein binding, F:signal transducer activity, P:actin filament organization, P:antigen receptor-mediated signaling pathway, P:B cell receptor signaling pathway, P:cell adhesion, P:cell chemotaxis, P:cell migration, P:cellular response to hepatocyte growth factor stimulus, P:epidermal growth factor receptor signaling pathway, P:G-protein coupled receptor signaling pathway, P:hepatocyte growth factor receptor signaling pathway, P:insulin receptor signaling pathway, P:integrin-mediated signaling pathway, P:neurotrophin TRK receptor signaling pathway, P:platelet-derived growth factor receptor signaling pathway, P:positive regulation of cell migration, P:positive regulation of endothelial cell migration, P:vascular endothelial growth factor receptor signaling pathway, C:cytoplasm, C:focal adhesion, C:lamellipodium, C:ruffle, F:signal transducer activity, P:actin filament organization, P:antigen receptor-mediated signaling pathway, P:B cell receptor signaling pathway, P:cell migration, P:epidermal growth factor receptor signaling pathway, P:G-protein coupled receptor signaling pathway, P:insulin receptor signaling pathway, P:integrin-mediated signaling pathway, P:neurotrophin TRK receptor signaling pathway, P:platelet-derived growth factor receptor signaling pathway, P:positive regulation of cell migration, C:cytoplasm, C:focal adhesion, C:lamellipodium, C:ruffle, F:signal transducer activity, P:actin filament organization, P:antigen receptor-mediated signaling pathway, P:B cell receptor signaling pathway, P:cell migration, P:epidermal growth factor receptor signaling pathway, P:G-protein coupled receptor signaling pathway, P:insulin receptor signaling pathway, P:integrin-mediated signaling pathway, P:neurotrophin TRK receptor signaling pathway, P:platelet-derived growth factor receptor signaling pathway, P:positive regulation of cell migration, C:cytoplasm, C:focal adhesion, C:lamellipodium, C:ruffle, F:signal transducer activity, P:actin filament organization, P:antigen receptor-mediated signaling pathway, P:B cell receptor signaling pathway, P:cell migration, P:epidermal growth factor receptor signaling pathway, P:G-protein coupled receptor signaling pathway, P:insulin receptor signaling pathway, P:integrin-mediated signaling pathway, P:neurotrophin TRK receptor signaling pathway, P:platelet-derived growth factor receptor signaling pathway, P:positive regulation of cell migration
UniProtAcetylation, Alternative splicing, Cell adhesion, Cell junction, Complete proteome, Cytoplasm, Phosphoprotein, Reference proteome, SH3 domain, SH3-binding
PADBCell shape (cytoskeleton, cell adhesion, morphology, cell junction, cellular structures, extracellular matrix)

Studies, tissues and diseases

Study IDSpeciesTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp24569379Mus musculuskidneyendothelial cellsAKI (AKI)2.10.00000148RNA microarray24569379

Compile date 08-10-2018© iMODE-CKD consortium