CKDdb-logoCKDdb - Molecule ID A0885

geneCKS2
nameCyclin-dependent kinases regulatory subunit 2
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
CKS2_HUMANP33552ENSG000001239751164Hs.83758116901

Functions and classifications

GOF:cyclin-dependent protein serine/threonine kinase regulator activity, P:cell division, P:cell proliferation, P:meiosis I, P:phosphatidylinositol-mediated signaling, P:regulation of cyclin-dependent protein serine/threonine kinase activity, P:spindle organization, F:cyclin-dependent protein kinase regulator activity, P:regulation of cyclin-dependent protein kinase activity, P:cell cycle
UniProt3D-structure, Acetylation, Cell cycle, Cell division, Complete proteome, Reference proteome
PADBcell cycle (turnover, mitosis, meiosis)

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp17003339aMus musculus24kidneyglomeruliDiabetes (diabetic nephropathy)1.19< 0.05cDNA microarray17003339
Exp17003339bMus musculus24kidneyglomeruliDiabetes (diabetic nephropathy)1.96< 0.05cDNA microarray17003339
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)2.110.0114RNA microarray19698090
Exp21752957bHomo sapiens22kidneytubuliDiabetes (diabetic kidney disease)3.7< 0.05RNA microarray21752957
Exp23757392aRattus norvegicus17kidneywholeDiabetes (diabetic nephropathy)2.77< 0.05RNA-seq23757392
Exp23757392bRattus norvegicus13kidneywholeDiabetes (diabetic nephropathy)2.5< 0.05RNA-seq23757392

Compile date 08-10-2018© iMODE-CKD consortium