CKDdb-logoCKDdb - Molecule ID A0880

geneCASP10, MCH4
nameCaspase-10 precursor
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
CASPA_HUMANQ92851ENSG00000003400843Hs.5353601762, 603909, 605027, 613659

Functions and classifications

GOC:cytosol, C:plasma membrane, C:ripoptosome, F:cysteine-type endopeptidase activity, P:apoptotic signaling pathway, P:innate immune response, P:positive regulation of I-kappaB kinase/NF-kappaB signaling, P:proteolysis, P:regulation of apoptotic process, P:apoptotic process, P:induction of apoptosis, P:positive regulation of I-kappaB kinase/NF-kappaB cascade
UniProtAlternative splicing, Apoptosis, Complete proteome, Direct protein sequencing, Disease mutation, Hydrolase, Polymorphism, Protease, Reference proteome, Repeat, Thiol protease, Zymogen, Phosphoprotein
PADBenzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19698090aHomo sapiens17bloodmononuclear cellsChronic_Renal_Insufficiency (Chronic kidney disease)0.380.0179406RNA microarray19698090
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.250.00032RNA microarray19698090
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.260.0000809RNA microarray19698090
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.340.000425RNA microarray19698090
Exp23505438aHomo sapiens kidneyproximal tubular cellsDiabetes (diabetic nephropathy)0.740.014cDNA microarray23505438

Compile date 08-10-2018© iMODE-CKD consortium