CKDdb-logoCKDdb - Molecule ID A0842

geneAKAP13, BRX, HT31
nameA-kinase anchoring protein 13
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
AKP13_HUMANQ12802ENSG0000017077611214Hs.459211604686

Functions and classifications

GOC:cytosol, C:membrane, C:nucleus, C:perinuclear region of cytoplasm, F:cAMP-dependent protein kinase activity, F:metal ion binding, F:Rho guanyl-nucleotide exchange factor activity, F:signal transducer activity, P:apoptotic signaling pathway, P:neurotrophin TRK receptor signaling pathway, P:nuclear export, P:positive regulation of apoptotic process, P:regulation of cardiac muscle hypertrophy, P:regulation of glucocorticoid mediated signaling pathway, P:regulation of protein kinase activity, P:regulation of Rho GTPase activity, P:small GTPase mediated signal transduction, F:kinase activity, C:cytoplasm, P:intracellular signal transduction, F:phospholipid binding, P:apoptotic process, P:nerve growth factor receptor signaling pathway, P:regulation of Rho protein signal transduction, P:regulation of small GTPase mediated signal transduction, C:intracellular
UniProt3D-structure, Alternative splicing, Coiled coil, Complete proteome, Cytoplasm, Guanine-nucleotide releasing factor, Membrane, Metal-binding, Nucleus, Phosphoprotein, Polymorphism, Proto-oncogene, Reference proteome, Zinc, Zinc-finger, Kinase, Transferase
PADBenzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp20019191Homo sapiens18kidneyglomeruliNephrosclerosis (glomerulosclerosis)3.613.23E-06RNA microarray20019191
Exp23935909Homo sapiens24bloodmonocytesChronic_Renal_Insufficiency (Chronic kidney disease)3.870.0054243RNA microarray23935909

Compile date 08-10-2018© iMODE-CKD consortium