CKDdb-logoCKDdb - Molecule ID A0691

geneAP1S1, AP19, CLAPS1
nameAdapter-related protein complex 1 sigma 1A subunit
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
AP1S1_HUMANP61966ENSG000001063671174Hs.489365603531, 609313

Functions and classifications

GOC:AP-1 adaptor complex, C:coated pit, C:cytosol, C:lysosomal membrane, C:trans-Golgi network membrane, F:protein transporter activity, P:antigen processing and presentation of exogenous peptide antigen via MHC class II, P:intracellular protein transport, P:post-Golgi vesicle-mediated transport, P:receptor-mediated endocytosis, P:regulation of defense response to virus by virus, P:response to virus, P:viral process, C:membrane coat, P:vesicle-mediated transport, P:cellular membrane organization, P:viral reproduction
UniProtAlternative splicing, Coated pit, Complete proteome, Cytoplasmic vesicle, Deafness, Golgi apparatus, Ichthyosis, Membrane, Mental retardation, Neuropathy, Phosphoprotein, Protein transport, Reference proteome, Transport, Endocytosis
PADBtransport, storage, endocytosis, exocytosis, vesicles

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp18354378Homo sapiens8kidneyepithelial cellsureteral_obstruction (unilateral ureteral obstruction)0.233 +/- 1.636< 0.05RNA microarray18354378
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.280.000237RNA microarray19698090
Exp21752957aHomo sapiens22kidneytubuliDiabetes (diabetic kidney disease)0.31< 0.05RNA microarray21752957

Compile date 08-10-2018© iMODE-CKD consortium