CKDdb-logoCKDdb - Molecule ID A0689

geneAP1M2
nameAdaptor-related protein complex 1
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
AP1M2_HUMANQ9Y6Q5ENSG0000012935410053Hs.18894607309

Functions and classifications

GOC:clathrin adaptor complex, C:clathrin-coated vesicle membrane, C:cytoplasmic vesicle membrane, C:cytosol, C:Golgi membrane, C:lysosomal membrane, C:trans-Golgi network membrane, P:antigen processing and presentation of exogenous peptide antigen via MHC class II, P:post-Golgi vesicle-mediated transport, P:protein targeting, P:regulation of defense response to virus by virus, P:vesicle targeting, P:viral process, P:intracellular protein transport, P:vesicle-mediated transport, P:cellular membrane organization, P:viral reproduction
UniProtAlternative splicing, Complete proteome, Cytoplasmic vesicle, Golgi apparatus, Membrane, Phosphoprotein, Protein transport, Reference proteome, Transport
PADBtransport, storage, endocytosis, exocytosis, vesicles

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19346236Homo sapiens10kidneycystsPolycystic_Kidney_Disease (Autosomal dominant polycystic kidney disease)0.040.005mRNA microarray19346236
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.310.0000287RNA microarray19698090
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.410.00499RNA microarray19698090
Exp21752957bHomo sapiens22kidneytubuliDiabetes (diabetic kidney disease)3.99< 0.05RNA microarray21752957
Exp21752957bHomo sapiens22kidneytubuliDiabetes (diabetic kidney disease)4.16< 0.05RNA microarray21752957
Exp23935909Homo sapiens24bloodmonocytesChronic_Renal_Insufficiency (Chronic kidney disease)0.310.0054961RNA microarray23935909
Exp26317775bHomo sapiens8kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)7.110.014278RNA microarray26317775

Compile date 08-10-2018© iMODE-CKD consortium