CKDdb-logoCKDdb - Molecule ID A0681

geneADRA2B, ADRA2L1, ADRA2RL1
nameAlpha-2B adrenergic receptor
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ADA2B_HUMANP18089ENSG00000222040151Hs.247686104260

Functions and classifications

GOC:integral component of plasma membrane, F:alpha2-adrenergic receptor activity, F:epinephrine binding, P:activation of MAPK activity by adrenergic receptor signaling pathway, P:activation of protein kinase B activity, P:angiogenesis, P:cell-cell signaling, P:epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway, P:female pregnancy, P:MAPK cascade, P:negative regulation of epinephrine secretion, P:negative regulation of norepinephrine secretion, P:platelet activation, P:positive regulation of blood pressure, P:positive regulation of neuron differentiation, P:positive regulation of uterine smooth muscle contraction, P:regulation of vascular smooth muscle contraction, C:integral component of membrane, C:plasma membrane, P:activation of MAPK activity, P:adrenergic receptor signaling pathway, C:integral to plasma membrane, C:integral to membrane
UniProt3D-structure, Cell membrane, Complete proteome, Disulfide bond, G-protein coupled receptor, Lipoprotein, Membrane, Palmitate, Polymorphism, Receptor, Reference proteome, Transducer, Transmembrane, Transmembrane helix
PADBreceptor

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.20.000411RNA microarray19698090

Compile date 08-10-2018© iMODE-CKD consortium