CKDdb-logoCKDdb - Molecule ID A0680

geneADRB3, ADRB3R, B3AR
nameBeta-3 adrenergic receptor
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ADRB3_HUMANP13945ENSG00000188778155Hs.2549109691

Functions and classifications

GOC:integral component of plasma membrane, C:nucleus, C:receptor complex, F:beta3-adrenergic receptor activity, F:epinephrine binding, F:norepinephrine binding, F:protein homodimerization activity, P:activation of adenylate cyclase activity, P:adenylate cyclase-activating G-protein coupled receptor signaling pathway, P:adenylate cyclase-modulating G-protein coupled receptor signaling pathway, P:aging, P:brown fat cell differentiation, P:carbohydrate metabolic process, P:diet induced thermogenesis, P:eating behavior, P:energy reserve metabolic process, P:heat generation, P:negative regulation of multicellular organism growth, P:positive regulation of MAPK cascade, P:response to antibiotic, P:response to cold, P:vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure, C:integral component of membrane, C:plasma membrane, F:beta-adrenergic receptor activity, P:adrenergic receptor signaling pathway, C:integral to plasma membrane, C:integral to membrane
UniProt3D-structure, Cell membrane, Complete proteome, Diabetes mellitus, Disulfide bond, G-protein coupled receptor, Glycoprotein, Lipoprotein, Membrane, Obesity, Palmitate, Polymorphism, Receptor, Reference proteome, Transducer, Transmembrane, Transmembrane helix
PADBreceptor

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp17579666cMus musculus6 to 12kidneywholeremnant_kidney_model (remnant kidney model)4.270.05RNA microarray17579666
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.210.00057RNA microarray19698090
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.380.0119RNA microarray19698090

Compile date 08-10-2018© iMODE-CKD consortium