CKDdb-logoCKDdb - Molecule ID A0660

geneACTR1A, CTRN1
nameAlpha-centractin
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ACTZ_HUMANP61163ENSP0000035892110121Hs.153961605143

Functions and classifications

GOC:centrosome, C:cytosol, C:dynactin complex, F:ATP binding, P:antigen processing and presentation of exogenous peptide antigen via MHC class II, P:G2/M transition of mitotic cell cycle, P:vesicle-mediated transport, C:cytoplasm, C:cytoskeleton
UniProtAcetylation, ATP-binding, Complete proteome, Cytoplasm, Cytoskeleton, Direct protein sequencing, Nucleotide-binding, Reference proteome
PADBCS: Cell shape (cytoskeleton, cell adhesion, morphology, cell junction, cellular structures, extracellular matrix)

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp18850734Canis lupus familiaris kidneydistal renal tubular cellskidney_calculi (Calcium oxalate monohydrate in vitro model)0.710.046Q-TOF MS/MS18850734
Exp20093355Homo sapiens33kidney Fibrosis (Interstitial fibrosis and tubular atrophy)down MS/MS, LTQ LX linear ion trap20093355
Exp21752957aHomo sapiens22kidneytubuliDiabetes (diabetic kidney disease)2.9< 0.05RNA microarray21752957
Exp22061828Rattus norvegicus kidney Gentamicin_induced (Gentamicin-induced nephropathy)0.41.90E-04Nano RP-LC, MALDI-TOF22061828
Exp24172336Mus musculus6kidneycortexAKI (AKI)2.40.003196058LC-MS/MS24172336
Exp24316357Rattus norvegicus kidneyproximal tubule cellsureteral_obstruction (kidney obstruction in vitro model)0.330.00341556LC-MS/MS24316357
Exp26317775aHomo sapiens53kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)0.465.11E-04RNA microarray26317775

Compile date 08-10-2018© iMODE-CKD consortium