CKDdb-logoCKDdb - Molecule ID A0586

geneAdora2b
nameAdenosine receptor A2b
speciesMus musculus

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGene
AA2BR_MOUSEQ60614ENSMUSG0000001850011541Mm.40740

Functions and classifications

GOC:integral component of membrane, C:plasma membrane, F:G-protein coupled adenosine receptor activity, F:G-protein coupled receptor activity, P:adenylate cyclase-activating G-protein coupled receptor signaling pathway, P:cellular response to extracellular stimulus, P:positive regulation of cAMP biosynthetic process, P:positive regulation of cGMP biosynthetic process, P:positive regulation of chemokine production, P:positive regulation of chronic inflammatory response to non-antigenic stimulus, P:positive regulation of guanylate cyclase activity, P:positive regulation of interleukin-6 production, P:positive regulation of mast cell degranulation, P:positive regulation vascular endothelial growth factor production, P:relaxation of vascular smooth muscle, C:cell surface, C:integral to membrane, P:negative regulation of cell proliferation, P:negative regulation of collagen biosynthetic process, P:positive regulation of cell proliferation, P:positive regulation of norepinephrine secretion, P:positive regulation of steroid biosynthetic process, P:positive regulation of vasodilation, P:regulation of angiogenesis
UniProtCell membrane, Complete proteome, Disulfide bond, G-protein coupled receptor, Glycoprotein, Lipoprotein, Membrane, Palmitate, Receptor, Reference proteome, Transducer, Transmembrane, Transmembrane helix
PADBreceptor

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp21411733bMus musculus11macrophageF4/80hi cellsGlomerulonephritis (lupus nephritis)0.360cDNA microarray21411733

Compile date 08-10-2018© iMODE-CKD consortium