CKDdb-logoCKDdb - Molecule ID A0574

geneAGFG1, HRB, RAB
nameNucleoporin-like protein RIP
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
AGFG1_HUMANP52594ENSG000001737443267Hs.352962600862

Functions and classifications

GOC:cytoplasmic membrane-bounded vesicle, C:Golgi apparatus, C:nuclear pore, F:ARF GTPase activator activity, F:DNA binding, F:RNA binding, F:zinc ion binding, P:cell differentiation, P:mRNA export from nucleus, P:multicellular organismal development, P:positive regulation of GTPase activity, P:regulation of ARF GTPase activity, P:spermatogenesis, F:metal ion binding, C:cell projection, C:neuronal cell body, P:acrosome assembly, P:intermediate filament organization, P:spermatid nucleus differentiation
UniProt3D-structure, Alternative splicing, Complete proteome, Cytoplasmic vesicle, Developmental protein, Differentiation, DNA-binding, Glycoprotein, Metal-binding, mRNA transport, Nucleus, Phosphoprotein, Reference proteome, Repeat, Spermatogenesis, Transport, Zinc, Zinc-finger
PADBtransport, storage, endocytosis, exocytosis, vesicles

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp21752957aHomo sapiens22kidneytubuliDiabetes (diabetic kidney disease)3.38< 0.05RNA microarray21752957
Exp23760282bMus musculus kidneywholeureteral_obstruction (renal tubulointerstitial injury)5.890.015RNA microarray23760282
Exp23935909Homo sapiens24bloodmonocytesChronic_Renal_Insufficiency (Chronic kidney disease)0.460.013013RNA microarray23935909
Exp26317775aHomo sapiens53kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)0.426.31E-05RNA microarray26317775

Compile date 08-10-2018© iMODE-CKD consortium