CKDdb-logoCKDdb - Molecule ID A0556

geneATP2A3
nameSarcoplasmic/endoplasmic reticulum calcium ATPase 3
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
AT2A3_HUMANQ93084ENSG00000074370489Hs.513870601929

Functions and classifications

GOC:endoplasmic reticulum membrane, C:integral component of membrane, C:nuclear membrane, C:platelet dense tubular network membrane, C:sarcoplasmic reticulum, C:sarcoplasmic reticulum membrane, F:ATP binding, F:calcium-transporting ATPase activity, F:metal ion binding, P:blood coagulation, P:ATP catabolic process, P:calcium ion transmembrane transport, C:integral to membrane, P:ATP biosynthetic process
UniProtAcetylation, Alternative splicing, ATP-binding, Calcium, Calcium transport, Complete proteome, Direct protein sequencing, Endoplasmic reticulum, Hydrolase, Ion transport, Magnesium, Membrane, Metal-binding, Nucleotide-binding, Nucleus, Phosphoprotein, Polymorphism, Reference proteome, Sarcoplasmic reticulum, Transmembrane, Transmembrane helix, Transport
PADBenzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.330.00175RNA microarray19698090
Exp20019191Homo sapiens18kidneyglomeruliNephrosclerosis (glomerulosclerosis)2.877.14E-06RNA microarray20019191
Exp23809614aHomo sapiens83bloodwholeChronic_Renal_Insufficiency (End-stage renal failure)0.161.90E-20RNA microarray23809614
Exp23809614bHomo sapiens32bloodwholeChronic_Renal_Insufficiency (End-stage renal failure)0.11.73E-13RNA microarray23809614
Exp25770168Homo sapiens17bloodmononuclear cellsGlomerulonephritis (IgA nephropathy)0.190.004RNA microarray25770168
Exp26317775bHomo sapiens8kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)3.440.015133RNA microarray26317775

Compile date 08-10-2018© iMODE-CKD consortium