CKDdb-logoCKDdb - Molecule ID A0550

geneBag3, Bis, mg638
nameBAG family molecular chaperone regulator 3
speciesMus musculus

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
BAG3_MOUSEQ9JLV1ENSMUSG0000003084729810Mm.84073603883, 612954, 613881

Functions and classifications

GOC:cytosol, C:neuron projection, C:plasma membrane, C:Z disc, F:protein binding, F:protein complex binding, P:brain development, P:cellular response to mechanical stimulus, P:extrinsic apoptotic signaling pathway in absence of ligand, P:extrinsic apoptotic signaling pathway via death domain receptors, P:negative regulation of striated muscle cell apoptotic process, P:protein stabilization, P:spinal cord development, C:cytosol, C:Z disc, F:protein binding, F:protein complex binding, P:cellular response to mechanical stimulus, P:extrinsic apoptotic signaling pathway in absence of ligand, P:extrinsic apoptotic signaling pathway via death domain receptors, P:negative regulation of striated muscle cell apoptotic process, P:protein stabilization, C:cytosol, C:Z disc, F:protein binding, F:protein complex binding, P:cellular response to mechanical stimulus, P:extrinsic apoptotic signaling pathway in absence of ligand, P:extrinsic apoptotic signaling pathway via death domain receptors, P:negative regulation of striated muscle cell apoptotic process, P:protein stabilization
UniProt3D-structure, Acetylation, Apoptosis, Chaperone, Complete proteome, Phosphoprotein, Reference proteome, Repeat
PADBchaperone, chaperonin

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp24569379Mus musculus kidneyendothelial cellsAKI (AKI)2.210.00000422RNA microarray24569379
Exp26317775bHomo sapiens8kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)3.20.013999RNA microarray26317775

Compile date 08-10-2018© iMODE-CKD consortium