CKDdb-logoCKDdb - Molecule ID A0549

geneBnip3
nameBCL2/adenovirus E1B 19 kDa-interacting protein 3
speciesRattus norvegicus

Molecule reference

UniProtEnsEMBLGeneIDUniGene
Q9ET45ENSRNOG0000001724384480Rn.2060

Functions and classifications

GOC:cytoplasm, C:dendrite, C:endoplasmic reticulum, C:integral component of mitochondrial outer membrane, C:mitochondrial membrane, C:mitochondrial outer membrane, C:mitochondrion, C:nuclear envelope, C:nucleoplasm, C:nucleus, F:protein homodimerization activity, P:apoptotic DNA fragmentation, P:autophagic cell death, P:brown fat cell differentiation, P:cell death, P:cellular response to cobalt ion, P:cellular response to hydrogen peroxide, P:cellular response to mechanical stimulus, P:chromatin remodeling, P:defense response to virus, P:granzyme-mediated apoptotic signaling pathway, P:intrinsic apoptotic signaling pathway in response to hypoxia, P:mitochondrial fragmentation involved in apoptotic process, P:mitochondrial outer membrane permeabilization, P:mitochondrial protein catabolic process, P:negative regulation of membrane potential, P:negative regulation of mitochondrial fusion, P:neuron apoptotic process, P:positive regulation of apoptotic process, P:positive regulation of mitochondrial fission, P:positive regulation of programmed cell death, P:positive regulation of protein complex disassembly, P:positive regulation of release of cytochrome c from mitochondria, P:reactive oxygen species metabolic process, P:regulation of mitochondrial membrane permeability, P:response to hyperoxia, P:response to hypoxia, C:integral to mitochondrial outer membrane, P:cellular response to hypoxia, P:induction of apoptosis, C:integral component of membrane, C:mitochondrial envelope, P:positive regulation of apoptotic process
UniProtComplete proteome, Reference proteome,
PADBunknown

Studies, tissues and diseases

Study IDSpeciesTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp23291264bRattus norvegicuskidneyproximal tubulecisplatin_induced (cisplatin-induced nephrotoxicity)0.30.000851RNA microarray23291264

Compile date 08-10-2018© iMODE-CKD consortium