CKDdb-logoCKDdb - Molecule ID A0483

geneBID
nameBH3 interacting domain death agonist
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
BID_HUMANP55957ENSG00000015475637Hs.591054601997

Functions and classifications

GOC:cytosol, C:integral component of mitochondrial membrane, C:mitochondrial outer membrane, F:death receptor binding, P:activation of cysteine-type endopeptidase activity involved in apoptotic process, P:brain development, P:establishment of protein localization to membrane, P:extrinsic apoptotic signaling pathway via death domain receptors, P:glial cell apoptotic process, P:intrinsic apoptotic signaling pathway, P:neuron apoptotic process, P:positive regulation of apoptotic process, P:positive regulation of extrinsic apoptotic signaling pathway, P:positive regulation of intrinsic apoptotic signaling pathway, P:positive regulation of mitochondrial outer membrane permeabilization, P:positive regulation of protein homooligomerization, P:positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway, P:positive regulation of release of cytochrome c from mitochondria, P:protein homooligomerization, P:protein targeting to mitochondrion, P:regulation of cell proliferation, P:regulation of G1/S transition of mitotic cell cycle, P:regulation of mitochondrial membrane permeability involved in apoptotic process, P:release of cytochrome c from mitochondria, P:response to estradiol, P:signal transduction in response to DNA damage, P:extrinsic apoptotic signaling pathway, C:cytoplasm, C:integral to mitochondrial membrane, P:regulation of mitochondrial membrane permeability, P:response to estradiol stimulus
UniProt3D-structure, Acetylation, Alternative splicing, Apoptosis, Complete proteome, Cytoplasm, Membrane, Mitochondrion, Phosphoprotein, Polymorphism, Reference proteome, Ubl conjugation
PADBsignalling

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)2.280.0000671RNA microarray19698090
Exp20019191Homo sapiens18kidneyglomeruliNephrosclerosis (glomerulosclerosis)3.163.23E-06RNA microarray20019191
Exp20543976Homo sapiens40urinewholeTransplantation (acute renal allograft rejection)0.2 LC-MS/MS20543976
Exp23505438aHomo sapiens kidneyproximal tubular cellsDiabetes (diabetic nephropathy)1.340.031cDNA microarray23505438

Compile date 08-10-2018© iMODE-CKD consortium