CKDdb-logoCKDdb - Molecule ID A0482

geneBIK, NBK
nameBcl-2 interacting killer
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
BIK_HUMANQ13323ENSG00000100290638Hs.475055603392

Functions and classifications

GOC:endomembrane system, C:integral component of membrane, C:mitochondrial membrane, P:apoptotic mitochondrial changes, P:apoptotic process, P:male gonad development, P:positive regulation of protein homooligomerization, P:positive regulation of release of cytochrome c from mitochondria, P:spermatogenesis, C:integral to membrane, P:induction of apoptosis
UniProt3D-structure, Apoptosis, Complete proteome, Membrane, Mitochondrion, Polymorphism, Reference proteome, Transmembrane, Transmembrane helix
PADBsignalling

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp17183245Homo sapiens24kidneyproximal tubuleproteinuria (proteinuric nephropathies)0.21< 0.05cDNA microarrays17183245
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.460.0152RNA microarray19698090
Exp23505438aHomo sapiens kidneyproximal tubular cellsDiabetes (diabetic nephropathy)1.370.018cDNA microarray23505438

Compile date 08-10-2018© iMODE-CKD consortium