CKDdb-logoCKDdb - Molecule ID A0481

geneBcl2l2
nameBcl-2-like protein 2
speciesMus musculus

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
B2CL2_MOUSEP70345ENSMUSG0000008968212050Mm.397611601931

Functions and classifications

GOC:cytosol, C:mitochondrial membrane, C:mitochondrial outer membrane, F:protein binding, F:protein heterodimerization activity, F:protein homodimerization activity, P:extrinsic apoptotic signaling pathway in absence of ligand, P:intrinsic apoptotic signaling pathway in response to DNA damage, P:negative regulation of apoptotic process, P:negative regulation of intrinsic apoptotic signaling pathway, P:Sertoli cell proliferation, P:apoptotic process
UniProtAcetylation, Alternative splicing, Apoptosis, Complete proteome, Membrane, Mitochondrion, Reference proteome
PADBsignalling

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp17579666aMus musculus6 to 12kidneywholeremnant_kidney_model (remnant kidney model)0.410.05RNA microarray17579666
Exp21752957bHomo sapiens22kidneytubuliDiabetes (diabetic kidney disease)0.23< 0.05RNA microarray21752957
Exp21752957bHomo sapiens22kidneytubuliDiabetes (diabetic kidney disease)0.33< 0.05RNA microarray21752957

Compile date 08-10-2018© iMODE-CKD consortium