CKDdb-logoCKDdb - Molecule ID A0480

geneBCL2A1, BCL2L5, BFL1
nameBcl-2-related protein A1
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
B2LA1_HUMANQ16548ENSG00000140379597Hs.227817601056

Functions and classifications

GOC:mitochondrial outer membrane, F:protein heterodimerization activity, F:protein homodimerization activity, P:extrinsic apoptotic signaling pathway in absence of ligand, P:intrinsic apoptotic signaling pathway in response to DNA damage, P:negative regulation of apoptotic process, P:negative regulation of intrinsic apoptotic signaling pathway, C:cytoplasm, P:apoptotic process
UniProt3D-structure, Alternative splicing, Apoptosis, Complete proteome, Cytoplasm, Polymorphism, Reference proteome
PADBsignalling

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp18187931aMus musculus20kidneyglomeruliGlomerulonephritis (lupus nephritis)43.8< 0.05RNA microarray18187931
Exp18187931bMus musculus18kidneyglomeruliGlomerulonephritis (lupus nephritis)30.8< 0.05RNA microarray18187931
Exp19698090aHomo sapiens17bloodmononuclear cellsChronic_Renal_Insufficiency (Chronic kidney disease)2.520.0483706RNA microarray19698090
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)32.163.65E-09RNA microarray19698090
Exp21752957aHomo sapiens22kidneytubuliDiabetes (diabetic kidney disease)3.38< 0.05RNA microarray21752957
Exp23505438aHomo sapiens kidneyproximal tubular cellsDiabetes (diabetic nephropathy)2.590.005cDNA microarray23505438
Exp23505438bHomo sapiens kidneyproximal tubular cellsDiabetes (diabetic nephropathy)1.170.024cDNA microarray23505438
Exp23989031aMus musculus kidneycortexGlomerulonephritis (Glomerulonephritis)2.1< 0.01DNA microarray23989031
Exp23989031bMus musculus kidneycortexGlomerulonephritis (Glomerulonephritis)4.5< 0.01DNA microarray23989031
Exp24172336Mus musculus6kidneycortexAKI (AKI)10000.049762673LC-MS/MS24172336

Compile date 08-10-2018© iMODE-CKD consortium