CKDdb-logoCKDdb - Molecule ID A0452

geneCanx
nameCalnexin
speciesMus musculus

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
CALX_MOUSEP35564ENSMUSG0000002036812330Mm.248827114217

Functions and classifications

GOC:axon, C:dendrite cytoplasm, C:dendritic spine, C:endoplasmic reticulum, C:integral component of lumenal side of endoplasmic reticulum membrane, C:integral component of membrane, C:melanosome, C:membrane, C:neuronal cell body, C:protein complex, C:ribosome, F:calcium ion binding, F:protein binding, P:aging, P:chaperone-mediated protein folding, P:clathrin-mediated endocytosis, P:synaptic vesicle endocytosis, C:endoplasmic reticulum membrane, C:integral to lumenal side of endoplasmic reticulum membrane, C:rough endoplasmic reticulum, P:protein folding, C:integral to membrane
UniProtAcetylation, Calcium, Chaperone, Complete proteome, Disulfide bond, Endoplasmic reticulum, Lectin, Lipoprotein, Membrane, Metal-binding, Palmitate, Phosphoprotein, Reference proteome, Repeat, Signal, Transmembrane, Transmembrane helix
PADBchaperone, chaperonin

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp17579666cMus musculus6 to 12kidneywholeremnant_kidney_model (remnant kidney model)2.370.05RNA microarray17579666
Exp20093355Homo sapiens33kidney Fibrosis (Interstitial fibrosis and tubular atrophy)up MS/MS, LTQ LX linear ion trap20093355
Exp20543976Homo sapiens40urinewholeTransplantation (acute renal allograft rejection)0.3 LC-MS/MS20543976
Exp21544065aRattus norvegicus17kidney Diabetes (diabetic nephropathy in T1D)3.290.05MALDI-TOF/TOF21544065
Exp22595305aRattus norvegicus24kidney Glomerulonephritis (Passive Heymann nephritis)0.83< 0.05LC-MS/MS22595305
Exp22595305bRattus norvegicus24kidney Glomerulonephritis (Passive Heymann nephritis)0.26< 0.05LC-MS/MS22595305
Exp23385635Homo sapiens14bloodperipheral blood mononuclear cell (PBMC)Fabry (Fabry)0.7807017540.009MALDI-TOF MS23385635
Exp23671862aMus musculus8heartsectionDiabetes (Diabetic Cardiomyopathy)1.77< 0.05micro-liquid chromatography system + LTQ Velos ion trap mass spectrometer23671862
Exp23671862bMus musculus8heartsectionDiabetes (Diabetic Cardiomyopathy)0.64< 0.05micro-liquid chromatography system + LTQ Velos ion trap mass spectrometer23671862
Exp24316357Rattus norvegicus kidneyproximal tubule cellsureteral_obstruction (kidney obstruction in vitro model)0.560.00255191LC-MS/MS24316357
Exp26317775aHomo sapiens53kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)0.467.06E-04RNA microarray26317775
Exp26317775aHomo sapiens53kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)0.498.65E-04RNA microarray26317775

Compile date 08-10-2018© iMODE-CKD consortium