CKDdb-logoCKDdb - Molecule ID A0420

geneABLIM1, ABLIM, LIMAB1
nameActin-binding LIM protein 1
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ABLM1_HUMANO14639ENSG000000992043983Hs.438236602330

Functions and classifications

GOC:actin cytoskeleton, C:cytoplasm, F:actin binding, F:zinc ion binding, P:axon guidance, P:cytoskeleton organization, P:organ morphogenesis, P:visual perception, F:metal ion binding, P:positive regulation of transcription from RNA polymerase II promoter
UniProtActin-binding, Alternative splicing, Coiled coil, Complete proteome, Cytoplasm, Cytoskeleton, LIM domain, Metal-binding, Phosphoprotein, Polymorphism, Reference proteome, Repeat, Zinc
PADBCell shape (cytoskeleton, cell adhesion, morphology, cell junction, cellular structures, extracellular matrix)

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseBiomarkerFold change in diseaseP-valueDetectionMol. modificationValidationPubMed/DOI
Exp20019191Homo sapiens18kidneyglomeruliNephrosclerosis (glomerulosclerosis) 1.511.98E-05RNA microarray  20019191
Exp20847290Homo sapiens30kidneyglomeruliGlomerulonephritis (FSGS + COLL) 5.260.0211RNA microarray  20847290
Exp23935909Homo sapiens24bloodmonocytesChronic_Renal_Insufficiency (Chronic kidney disease) 3.880.0226705RNA microarray  23935909
Exp24927646aMus musculus16kidney Diabetes (diabetic nephropathy treated with Phlorizin) 0.58< 0.05LC-MS/MS  24927646
Exp24927646bMus musculus16kidney Diabetes (diabetic nephropathy) 0.38< 0.05LC-MS/MS  24927646

Compile date 08-30-2016© iMODE-CKD consortium