CKDdb-logoCKDdb - Molecule ID A0417

geneCAPZA2
nameF-actin capping protein alpha-2 subunit
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
CAZA2_HUMANP47755ENSG00000198898830Hs.446123601571

Functions and classifications

GOC:cortical cytoskeleton, C:cytosol, C:extracellular region, C:F-actin capping protein complex, C:membrane, C:WASH complex, P:actin cytoskeleton organization, P:actin filament capping, P:blood coagulation, P:cellular component movement, P:innate immune response, P:protein complex assembly, C:cytoplasm
UniProtAcetylation, Actin capping, Actin-binding, Complete proteome, Direct protein sequencing, Reference proteome
PADBCell shape (cytoskeleton, cell adhesion, morphology, cell junction, cellular structures, extracellular matrix)

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp18187931aMus musculus20kidneyglomeruliGlomerulonephritis (lupus nephritis)2.2< 0.05RNA microarray18187931
Exp19369687Mus musculus kidneyproximal tubule cellsCyclosporine_A_induced (Ciclosporine A in vitro model)2.08<0.0004MALDI TOF/TOF19369687
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)3.50.000000773RNA microarray19698090
Exp20093355Homo sapiens33kidney Fibrosis (Interstitial fibrosis and tubular atrophy)up MS/MS, LTQ LX linear ion trap20093355

Compile date 08-10-2018© iMODE-CKD consortium