CKDdb-logoCKDdb - Molecule ID A0410

geneATP6AP1, ATP6IP1, ATP6S1
nameV-type proton ATPase subunit S1
speciesHomo sapiens

Molecule reference


Functions and classifications

GOC:integral component of membrane, C:proton-transporting two-sector ATPase complex, C:proton-transporting V-type ATPase, V1 domain, C:vacuolar membrane, F:ATP binding, F:proton-transporting ATP synthase activity, rotational mechanism, F:proton-transporting ATPase activity, rotational mechanism, F:transporter activity, P:ATP catabolic process, P:ATP hydrolysis coupled proton transport, P:proton transport, "C:proton-transporting V-type ATPase, V1 domain, P:ATP hydrolysis coupled proton transport", "C:integral to membrane, F:hydrogen ion transporting ATP synthase activity, rotational mechanism, P:aging, P:cell death, P:cell death"
UniProtATP-binding, Complete proteome, Glycoprotein, Hydrogen ion transport, Ion transport, Membrane, Nucleotide-binding, Reference proteome, Signal, Transmembrane, Transmembrane helix, Transport, Vacuole
PADBTP: transport, storage, endocytosis, exocytosis, vesicles

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp26317775bHomo sapiens8kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)7.510.005547RNA microarray26317775

Compile date 08-10-2018© iMODE-CKD consortium