CKDdb-logoCKDdb - Molecule ID A040B

geneBCAS2, DAM1
namePre-mRNA-splicing factor SPF27
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
SPF27_HUMANO75934ENSG0000011675210286Hs.22960605783

Functions and classifications

GOC:nucleolus, C:spliceosomal complex, P:mRNA processing, P:RNA splicing, via transesterification reactions
UniProtAcetylation, Coiled coil, Complete proteome, Direct protein sequencing, mRNA processing, mRNA splicing, Nucleus, Polymorphism, Reference proteome, Spliceosome
PADBtranscription and translation, gene regulation

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)3.342.69E-09RNA microarray19698090
Exp24316357Rattus norvegicus kidneyproximal tubule cellsureteral_obstruction (kidney obstruction in vitro model)2.640.003777495LC-MS/MS24316357
Exp26317775aHomo sapiens53kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)0.454.11E-04RNA microarray26317775

Compile date 08-10-2018© iMODE-CKD consortium