CKDdb-logoCKDdb - Molecule ID A0408

geneATP6V0E, ATP6V0E1, ATP6H
nameV-type proton ATPase subunit E 1
speciesHomo sapiens

Molecule reference


Functions and classifications

GOC:endosome membrane, C:integral component of membrane, C:phagocytic vesicle membrane, C:proton-transporting V-type ATPase, V0 domain, F:proton-transporting ATPase activity, rotational mechanism, P:ATP hydrolysis coupled proton transport, P:cell growth, P:cellular iron ion homeostasis, P:insulin receptor signaling pathway, P:interaction with host, P:phagosome maturation, P:response to amino acid, P:transferrin transport, P:vacuolar acidification, C:proton-transporting V-type ATPase, V0 domain, F:hydrogen ion transmembrane transporter activity, P:ATP hydrolysis coupled proton transport, C:integral to membrane, C:vacuole, P:response to amino acid stimulus
UniProtComplete proteome, Hydrogen ion transport, Hydrolase, Ion transport, Membrane, Reference proteome, Transmembrane, Transmembrane helix, Transport
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp20019191Homo sapiens18kidneyglomeruliNephrosclerosis (glomerulosclerosis)3.511.25E-05RNA microarray20019191
Exp21752957bHomo sapiens22kidneytubuliDiabetes (diabetic kidney disease)4.37< 0.05RNA microarray21752957

Compile date 08-10-2018© iMODE-CKD consortium