CKDdb-logoCKDdb - Molecule ID A0401

geneATP6V1C1, ATP6C, ATP6D
nameVacuolar ATP synthase subunit C 1
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
VATC1_HUMANP21283ENSG00000155097528Hs.86905603097

Functions and classifications

GOC:apical part of cell, C:cytoplasmic vesicle, C:cytosol, C:lysosomal membrane, C:plasma membrane, C:proton-transporting two-sector ATPase complex, C:proton-transporting V-type ATPase, V1 domain, F:hydrogen-exporting ATPase activity, phosphorylative mechanism, F:proton-transporting ATPase activity, rotational mechanism, P:ATP hydrolysis coupled proton transport, P:cellular iron ion homeostasis, P:insulin receptor signaling pathway, P:interaction with host, P:phagosome maturation, P:transferrin transport, C:lysosomal membrane, F:hydrogen ion transmembrane transporter activity, P:ATP hydrolysis coupled proton transport, P:ATP catabolic process, C:proton-transporting V-type ATPase, V1 domain, F:hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
UniProtAcetylation, Complete proteome, Direct protein sequencing, Hydrogen ion transport, Ion transport, Reference proteome, Transport
PADBtransport, storage, endocytosis, exocytosis, vesicles

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.480.00299RNA microarray19698090
Exp26317775aHomo sapiens53kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)0.466.42E-04RNA microarray26317775

Compile date 08-10-2018© iMODE-CKD consortium