CKDdb-logoCKDdb - Molecule ID A0399

geneAtp6v1b1, Atp6v1b1_predicted
nameATPase
speciesRattus norvegicus

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
VATB1_HUMAND3ZZS8ENSRNOG00000013573312488Rn.103610192132, 267300

Functions and classifications

GOC:apical part of cell, C:apical plasma membrane, C:basolateral plasma membrane, C:cytosol, C:lateral plasma membrane, C:microvillus, C:proton-transporting V-type ATPase, V1 domain, C:vacuolar proton-transporting V-type ATPase complex, F:ATP binding, F:hydrogen ion transmembrane transporter activity, F:hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances, F:protein complex binding, P:ATP hydrolysis coupled proton transport, P:ATP metabolic process, P:calcium ion homeostasis, P:excretion, P:inner ear morphogenesis, P:ossification, P:pH reduction, P:proton transport, P:regulation of pH, P:sensory perception of sound
UniProtComplete proteome, Hydrogen ion transport, Ion transport, Reference proteome, Transport
PADBtransport, storage, endocytosis, exocytosis, vesicles

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp20813037cRattus norvegicus6kidneywholePolycystic_Kidney_Disease (polycystic kidney disease)0.495.93E-07RNA microarray20813037
Exp26317775bHomo sapiens8kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)8.190.004547RNA microarray26317775

Compile date 08-10-2018© iMODE-CKD consortium